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Histopathological findings at week 52 for rats treated with potassium octatitanate fibers ( TISMO ) (Experiment 2). (a, b) Lungs from Group 1 rats (treated with TISMO and N‐bis (2‐hydroxypropyl) nitrosamine (DHPN)) with HE staining. (b) Lungs from group 2 rats ( DHPN only). (c) Lungs from group 1 rats (DHPN and TISMO) with immunohistochemical staining for napsin A. (d) Lungs from group 1 rats (DHPN and TISMO) with immunohistochemical staining for <t>calretinin.</t> (e, f) Lungs from group 3 rats (TISMO only). In TISMO ‐treated groups 1 and 3, pleural thickening and atypical cells were observed in the lung (a, b, e, f). The invasive lesions in the lung of group 1 were observed but could not be distinguished as either mesotheliomas or bronchioloalveolar adenocarcinomas (a, b). The atypical cells in the lesions stained positive for napsin A (c) and negative for calretinin (d).
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Novocastra antimouse calretinin monoclonal antibody clone 5a5
Histopathological findings at week 52 for rats treated with potassium octatitanate fibers ( TISMO ) (Experiment 2). (a, b) Lungs from Group 1 rats (treated with TISMO and N‐bis (2‐hydroxypropyl) nitrosamine (DHPN)) with HE staining. (b) Lungs from group 2 rats ( DHPN only). (c) Lungs from group 1 rats (DHPN and TISMO) with immunohistochemical staining for napsin A. (d) Lungs from group 1 rats (DHPN and TISMO) with immunohistochemical staining for <t>calretinin.</t> (e, f) Lungs from group 3 rats (TISMO only). In TISMO ‐treated groups 1 and 3, pleural thickening and atypical cells were observed in the lung (a, b, e, f). The invasive lesions in the lung of group 1 were observed but could not be distinguished as either mesotheliomas or bronchioloalveolar adenocarcinomas (a, b). The atypical cells in the lesions stained positive for napsin A (c) and negative for calretinin (d).
Antimouse Calretinin Monoclonal Antibody Clone 5a5, supplied by Novocastra, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Journal: Cell Reports Medicine

Article Title: A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers

doi: 10.1016/j.xcrm.2024.101434

Figure Lengend Snippet:

Article Snippet: anti-PARP1 (mouse monoclonal antibody, Clone 5a5) , Santa Cruz Biotechnology , Cat# sc-56197; RRID: AB_630080.

Techniques: Derivative Assay, Recombinant, Western Blot, DC Protein Assay, Caspase-Glo Assay, Gene Expression, Mutagenesis, Software, Flow Cytometry, Imaging, Inverted Microscopy, Cytometry

Histopathological findings at week 52 for rats treated with potassium octatitanate fibers ( TISMO ) (Experiment 2). (a, b) Lungs from Group 1 rats (treated with TISMO and N‐bis (2‐hydroxypropyl) nitrosamine (DHPN)) with HE staining. (b) Lungs from group 2 rats ( DHPN only). (c) Lungs from group 1 rats (DHPN and TISMO) with immunohistochemical staining for napsin A. (d) Lungs from group 1 rats (DHPN and TISMO) with immunohistochemical staining for calretinin. (e, f) Lungs from group 3 rats (TISMO only). In TISMO ‐treated groups 1 and 3, pleural thickening and atypical cells were observed in the lung (a, b, e, f). The invasive lesions in the lung of group 1 were observed but could not be distinguished as either mesotheliomas or bronchioloalveolar adenocarcinomas (a, b). The atypical cells in the lesions stained positive for napsin A (c) and negative for calretinin (d).

Journal: Cancer Science

Article Title: Chronic mesothelial reaction and toxicity of potassium octatitanate fibers in the pleural cavity in mice and F344 rats

doi: 10.1111/cas.12944

Figure Lengend Snippet: Histopathological findings at week 52 for rats treated with potassium octatitanate fibers ( TISMO ) (Experiment 2). (a, b) Lungs from Group 1 rats (treated with TISMO and N‐bis (2‐hydroxypropyl) nitrosamine (DHPN)) with HE staining. (b) Lungs from group 2 rats ( DHPN only). (c) Lungs from group 1 rats (DHPN and TISMO) with immunohistochemical staining for napsin A. (d) Lungs from group 1 rats (DHPN and TISMO) with immunohistochemical staining for calretinin. (e, f) Lungs from group 3 rats (TISMO only). In TISMO ‐treated groups 1 and 3, pleural thickening and atypical cells were observed in the lung (a, b, e, f). The invasive lesions in the lung of group 1 were observed but could not be distinguished as either mesotheliomas or bronchioloalveolar adenocarcinomas (a, b). The atypical cells in the lesions stained positive for napsin A (c) and negative for calretinin (d).

Article Snippet: The anti‐mouse calretinin mAb (clone 5A5), purchased from Novocastra Laboratories (Newcastle Upon Tyne, UK), was used at 1:100 dilution.

Techniques: Staining, Immunohistochemical staining